Biotin-HPDP

Biotin-HPDP

Author: ApexBio

spu:

A8008

CAS:

129179-83-5

purity:

0.98

shortsummary:

Sulfhydryl-reactive biotinylation reagent, pyridyldithiol-activated

26305-03-3 Biological Activity

Synonyms:

BiotinHPDP

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Formula:

C24H37N5O3S3

M.Wt:

539.78

Chemical Name:

5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[6-[3-(pyridin-2-yldisulfanyl)propanoylamino]hexyl]pentanamide

SMILES:

C1C2C(C(S1)CCCCC(=O)NCCCCCCNC(=O)CCSSC3=CC=CC=N3)NC(=O)N2

Solubility:

insoluble in H2O; ≥101.4 mg/mL in DMSO; ≥8.29 mg/mL in EtOH with ultrasonic

Storage:

Store at -20°C

Physical Appearance:

A solid

DeliveryTime:

In stock

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ShippingType:

Blue ice

description:

Biotin-HPDP (N-[6-(biotinamido)hexyl]-3’-(2’-pyridyldithio)propionamide), a sulfhydryl-reactive biotinylation agent, is  a water-insoluble reagent that requires the dissolution of suitable solvents, including dimethyl sulfoxide (DMSO) and dimethylformamide (DMF),  prior to the addition into aqueous reactions. Biotin-HPDP consists of a bicyclic biotin rings structure, a 1,6-diaminohexane spacer group attached to the valeric acid side chain of biotin and a sulfhydryl-reactive group at the end of the spacer. The pyridyl disulfide group at the end of biotin-HPDP is able to react with free thiol groups on proteins and other molecules forming a disulfide bond and releasing pyridine-2-thione. The long spacer arm of biotin-HPDP enables the modified molecule to better bind to the avidin or streptavidin probes.

related websites:

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